pkpd.protocols.protocol_pkpd_dose_escalation module

pkpd.protocols.protocol_pkpd_dose_escalation.ClopperPearson(k, n, alpha=0.05)[source]
class pkpd.protocols.protocol_pkpd_dose_escalation.ProtPKPDDoseEscalation(**kwargs)[source]

Bases: pkpd.protocols.protocol_pkpd.ProtPKPD

Given a set of binary responses (toxicity, response/not response, …), estimate the next dose for a target response

Protocol created by http://www.kinestatpharma.com

bestOfFive()[source]
findDose(dose)[source]
getBeforeLastResponse()[source]
getCurrentDose()[source]
getLastResponse()[source]
getNextDose()[source]
getPreviousDose(n0=1)[source]
parseInput()[source]
runEstimate()[source]
storerBC()[source]
storerC()[source]
threePlusThree()[source]
upAndDown()[source]