pkpd.protocols.protocol_pkpd_dissolution_loo_riegelman_inverse module¶
- class pkpd.protocols.protocol_pkpd_dissolution_loo_riegelman_inverse.ProtPKPDDeconvolutionLooRiegelmanInverse(**kwargs)[source]¶
Bases:
pkpd.protocols.protocol_pkpd.ProtPKPD
Given a profile of amount absorbed, find the central and peripheral concentrations that gave raise to it. This is an inverse Loo-Riegelman problem.
The parameters of this protocol are defined as microconstants. Remind that k10=Cl*V, k12=Clp*V, k21=Clp*Vp